SKINDERMA Deoxycholic 10% - 5 x 10ml

SKINDERMA Deoxycholic 10% 5 x 10ml is a professional-grade lipolytic mesotherapy solution containing Sodium Deoxycholate 10% — a bile acid that destroys fat cell membranes, permanently eliminating their ability to store or accumulate fat. This targeted solution is particularly effective for reducing localized fat deposits, including the double chin (submental) area and other body contouring indications.

Key Benefits

• Destroys fat cells to permanently reduce localized fat deposits
• Prevents treated fat cells from storing or accumulating fat
• Highly effective for double chin (submental fat) reduction
• Supports body contouring and lipolysis protocols
• Minimally invasive alternative to surgical fat removal

Active Ingredient

• Sodium Deoxycholate (10%) — a naturally occurring secondary bile acid produced by intestinal bacteria from cholic acid, and normally present in the body as a fat emulsifier in the digestive system. When administered into adipose tissue via mesotherapy, Sodium Deoxycholate acts as a potent cytolytic agent — disrupting the phospholipid bilayer of adipocyte cell membranes, causing immediate cell lysis (adipocytolysis) and permanent destruction of the fat cells. Unlike enzymatic lipolytic agents (such as Lipase or L-Carnitine) which mobilize fat while leaving the adipocyte intact, Deoxycholate permanently destroys the fat cell itself, ensuring that treated cells cannot regenerate or re-accumulate fat. Following adipocytolysis, the released lipids and cellular debris trigger a controlled local inflammatory response, stimulating macrophage activity and lymphatic clearance to remove the destroyed cells and metabolize the released fatty acids. The result is a permanent, measurable reduction in fat volume in the treated area.

Treatment Area: Face & Body (double chin, abdomen, flanks, arms, thighs)
Recommended For: Localized fat deposits, double chin, body contouring lipolysis
Presentation: 5 x 10ml vials

How does Sodium Deoxycholate permanently destroy fat cells? Sodium Deoxycholate is a bile acid that acts as a cytolytic detergent — when administered into adipose tissue via mesotherapy, it disrupts the phospholipid bilayer of adipocyte cell membranes, causing immediate cell lysis. Unlike lipolytic agents that simply mobilize stored fat, Deoxycholate permanently destroys the adipocyte itself. The destroyed cells and released lipids are then cleared via macrophage activity and the lymphatic system, resulting in a permanent, measurable reduction of fat volume in the treated area.

What areas can be treated with Deoxycholic mesotherapy? The most common treatment area is the submental region (double chin), where Sodium Deoxycholate is clinically validated for submental fat reduction. It is also used in body contouring protocols for the abdomen, flanks, inner and outer thighs, arms, bra fat, and other localized fat deposits. Its permanent fat cell destruction mechanism makes it particularly effective for areas resistant to diet and exercise.

How does Deoxycholic acid compare to Lipase and other lipolytic agents? Lipase and L-Carnitine work by mobilizing and metabolizing stored fat within intact adipocytes — they reduce fat content but leave the fat cells alive and capable of re-accumulating fat if caloric intake increases. Sodium Deoxycholate permanently destroys the adipocyte membrane, eliminating the cell entirely. This makes Deoxycholate more aggressive, producing more pronounced and permanent results, but also requiring careful dosing and technique to avoid damage to surrounding non-adipose tissue.

Who is this product for? SKINDERMA Deoxycholic 10% is formulated for licensed aesthetic practitioners, dermatologists, and body contouring specialists performing professional lipolytic mesotherapy protocols. It is intended for professional clinic use only and requires precise application technique.

For professional use only. Not intended to diagnose, treat, cure, or prevent any disease.