SKINDERMA Asian Centella 20 x 5ml – Circulation & Skin Rejuvenation Microneedling Mesotherapy

SKINDERMA Asian Centella is a professional microneedling mesotherapy solution powered by Centella asiatica extract — a time-honoured botanical active with centuries of use in traditional medicine and a robust body of modern clinical research supporting its role in collagen synthesis, microvascular strengthening, wound healing, and tissue remodeling. This versatile formula is effective across face, body, and scalp protocols.

Key Benefits

• Improves blood circulation, especially in cellulite-affected areas
• Strengthens capillaries and veins for healthier skin tone and microvascular integrity
• Stimulates collagen synthesis and connective tissue remodeling
• Reduces the appearance of cellulite and stretch marks
• Supports hair loss, acne scar, and wound healing protocols
• Helps reduce wrinkles and improve overall skin texture and density

Active Ingredient

• Centella asiatica Extract — a standardized botanical extract rich in four primary bioactive triterpenoid compounds, each contributing distinct and synergistic mechanisms of action:
  
  Asiaticoside — a triterpene glycoside that stimulates fibroblast proliferation and collagen type I and III synthesis, and activates the TGF-β1 pathway to promote wound healing and tissue repair. Asiaticoside has been shown to increase collagen content in treated tissue and is a key driver of Centella’s established efficacy in stretch mark reduction, scar remodeling, and skin rejuvenation.
  
  Madecassoside — a triterpenoid with potent anti-inflammatory and antioxidant properties that protects skin cells from oxidative stress, inhibits pro-inflammatory cytokines, and supports the resolution of inflammation in acne scars, post-procedural skin, and cellulite-associated tissue inflammation. Madecassoside also stimulates collagen synthesis and supports epidermal repair.
  
  Asiatic Acid — directly stimulates fibroblast collagen synthesis and inhibits the activity of collagenase enzymes that degrade existing collagen, protecting the structural integrity of the extracellular matrix. Asiatic acid also inhibits keloid fibroblast proliferation, making it useful in hypertrophic scar and stretch mark protocols.
  
  Madecassic Acid — strengthens capillary walls and venous tone by stimulating the synthesis of collagen in blood vessel walls, improving microvascular integrity and reducing capillary fragility. This vascular-strengthening action directly improves local circulation in cellulite-affected tissue, reducing the vascular stasis and fluid accumulation that contribute to oedematous cellulite.

Treatment Area: Face, Neck, Body & Scalp
Recommended For: Cellulite, wrinkles, stretch marks, acne scars, hair loss, and skin rejuvenation
Presentation: 20 x 5ml ampoules

What is Centella asiatica and why is it used in mesotherapy? Centella asiatica is a botanical extract standardized for four triterpenoid compounds — asiaticoside, madecassoside, asiatic acid, and madecassic acid — each with clinically documented roles in collagen synthesis, inflammation resolution, microvascular strengthening, and tissue repair. In mesotherapy protocols, these compounds reach the dermis and subcutaneous tissue at therapeutic concentrations, stimulating fibroblast activity, improving local circulation, and remodeling connective tissue across a wide range of aesthetic indications.

How does Centella asiatica reduce cellulite? Centella addresses cellulite through two complementary mechanisms: its triterpenoids (particularly madecassic acid) strengthen capillary walls and improve microvascular tone, reducing the vascular stasis and fluid accumulation that drive oedematous cellulite; and its collagen-stimulating compounds (asiaticoside, asiatic acid) remodel the connective tissue matrix, improving skin firmness and reducing the structural laxity that allows fat to push through and create the dimpled appearance of cellulite.

What is the role of Centella asiatica in stretch mark and scar treatment? Centella asiatica is one of the most clinically validated botanicals for stretch mark (striae) prevention and reduction, and for hypertrophic scar remodeling. Asiaticoside stimulates collagen production in the damaged dermis, while asiatic acid inhibits excessive collagen cross-linking and keloid fibroblast activity — helping to normalize scar tissue and restore a more natural skin texture. Madecassoside’s anti-inflammatory action supports the resolution of the inflammatory phase in active stretch marks and post-procedural skin.

Who is this product for? SKINDERMA Asian Centella is formulated for licensed aesthetic practitioners, dermatologists, trichologists, and skin clinics performing professional mesotherapy and microneedling protocols for cellulite, skin rejuvenation, scar remodeling, and hair loss. 

Professional use only. Not intended to diagnose, treat, cure, or prevent any disease.