{"product_id":"skinderma-asian-centella-ampoules-20-x-5ml","title":"SKINDERMA Asian Centella 20 x 5ml – Circulation \u0026 Skin Rejuvenation Microneedling Mesotherapy","description":"\u003cp\u003eSKINDERMA Asian Centella is a professional microneedling mesotherapy solution powered by \u003cstrong\u003eCentella asiatica extract\u003c\/strong\u003e — a time-honoured botanical active with centuries of use in traditional medicine and a robust body of modern clinical research supporting its role in collagen synthesis, microvascular strengthening, wound healing, and tissue remodeling. This versatile formula is effective across face, body, and scalp protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eImproves blood circulation, especially in cellulite-affected areas\u003c\/li\u003e\n\u003cli\u003eStrengthens capillaries and veins for healthier skin tone and microvascular integrity\u003c\/li\u003e\n\u003cli\u003eStimulates collagen synthesis and connective tissue remodeling\u003c\/li\u003e\n\u003cli\u003eReduces the appearance of cellulite and stretch marks\u003c\/li\u003e\n\u003cli\u003eSupports hair loss, acne scar, and wound healing protocols\u003c\/li\u003e\n\u003cli\u003eHelps reduce wrinkles and improve overall skin texture and density\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentella asiatica Extract\u003c\/strong\u003e — a standardized botanical extract rich in four primary bioactive triterpenoid compounds, each contributing distinct and synergistic mechanisms of action: \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eAsiaticoside\u003c\/strong\u003e — a triterpene glycoside that stimulates fibroblast proliferation and collagen type I and III synthesis, and activates the TGF-β1 pathway to promote wound healing and tissue repair. Asiaticoside has been shown to increase collagen content in treated tissue and is a key driver of Centella’s established efficacy in stretch mark reduction, scar remodeling, and skin rejuvenation. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eMadecassoside\u003c\/strong\u003e — a triterpenoid with potent anti-inflammatory and antioxidant properties that protects skin cells from oxidative stress, inhibits pro-inflammatory cytokines, and supports the resolution of inflammation in acne scars, post-procedural skin, and cellulite-associated tissue inflammation. Madecassoside also stimulates collagen synthesis and supports epidermal repair. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eAsiatic Acid\u003c\/strong\u003e — directly stimulates fibroblast collagen synthesis and inhibits the activity of collagenase enzymes that degrade existing collagen, protecting the structural integrity of the extracellular matrix. Asiatic acid also inhibits keloid fibroblast proliferation, making it useful in hypertrophic scar and stretch mark protocols. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eMadecassic Acid\u003c\/strong\u003e — strengthens capillary walls and venous tone by stimulating the synthesis of collagen in blood vessel walls, improving microvascular integrity and reducing capillary fragility. This vascular-strengthening action directly improves local circulation in cellulite-affected tissue, reducing the vascular stasis and fluid accumulation that contribute to oedematous cellulite.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face, Neck, Body \u0026amp; Scalp\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Cellulite, wrinkles, stretch marks, acne scars, hair loss, and skin rejuvenation\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Centella asiatica and why is it used in mesotherapy?\u003c\/strong\u003e Centella asiatica is a botanical extract standardized for four triterpenoid compounds — asiaticoside, madecassoside, asiatic acid, and madecassic acid — each with clinically documented roles in collagen synthesis, inflammation resolution, microvascular strengthening, and tissue repair. In mesotherapy protocols, these compounds reach the dermis and subcutaneous tissue at therapeutic concentrations, stimulating fibroblast activity, improving local circulation, and remodeling connective tissue across a wide range of aesthetic indications.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Centella asiatica reduce cellulite?\u003c\/strong\u003e Centella addresses cellulite through two complementary mechanisms: its triterpenoids (particularly madecassic acid) strengthen capillary walls and improve microvascular tone, reducing the vascular stasis and fluid accumulation that drive oedematous cellulite; and its collagen-stimulating compounds (asiaticoside, asiatic acid) remodel the connective tissue matrix, improving skin firmness and reducing the structural laxity that allows fat to push through and create the dimpled appearance of cellulite.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is the role of Centella asiatica in stretch mark and scar treatment?\u003c\/strong\u003e Centella asiatica is one of the most clinically validated botanicals for stretch mark (striae) prevention and reduction, and for hypertrophic scar remodeling. Asiaticoside stimulates collagen production in the damaged dermis, while asiatic acid inhibits excessive collagen cross-linking and keloid fibroblast activity — helping to normalize scar tissue and restore a more natural skin texture. Madecassoside’s anti-inflammatory action supports the resolution of the inflammatory phase in active stretch marks and post-procedural skin.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Asian Centella is formulated for licensed aesthetic practitioners, dermatologists, trichologists, and skin clinics performing professional mesotherapy and microneedling protocols for cellulite, skin rejuvenation, scar remodeling, and hair loss. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753040118074,"sku":"SKD 1039","price":78.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/asiancentella.jpg?v=1755598416","url":"https:\/\/www.mesotherapy.ca\/products\/skinderma-asian-centella-ampoules-20-x-5ml","provider":"Mesotherapy.ca","version":"1.0","type":"link"}